First trimester serum tests for Down's syndrome screening

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First-trimester screening for Down's syndrome.

The aim of the present study was to evaluate the efficacy of the first trimester screening for Down syndrome (DS) in an unselected low-risk Finnish population. The study involved 4,617 women who attended screening between the 8th and 14th weeks of pregnancy in 1998-2000. They gave a blood sample for the measurement of pregnancy associated plasma protein A (PAPP-A) and free beta human chorionic ...

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Effect of Shared Decision-making on Decisional Conflict and Uptake of First-trimester Screening Tests

Introduction: Several factors influence women’s decision to take First Trimester Screening (FTS) tests. These factors are associated with the ambivalence of women toward undergoing screening tests.  Objective: This study aimed to investigate the effect of Shared Decision-Making (SDM) about undergoing FTS on Decisional Conflict (DC) immediately after consultation and uptake of FTS. Materials a...

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First-trimester screening for Dandy-Walker syndrome using intracranial translucency

Methods During a 3-year period from 2012 and 2015, consecutive women undergoing first-trimester screening for aneuploidy were routine examined for the presence of the IT in the sagittal plane of the fetal head by one FMF-accredited MFM specialist. The anterior-posterior diameter was measured and normative data were generated. Fetuses with increased IT were further studied with serial scans and ...

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ADAM 12 as a first-trimester maternal serum marker in screening for Down syndrome.

BACKGROUND A Disintegrin And Metalloprotease 12 (ADAM 12) is a glycoprotein synthesised by placenta and it has been shown to be a potential first-trimester maternal serum marker for Down syndrome (DS) in two small series. Here we analyse further, the potential of ADAM 12 as a marker for DS in a large collection of first-trimester serum samples. MATERIALS AND METHODS The concentration of ADAM ...

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physicians and patients’ awareness of screening tests for the first trimester of pregnancy

conclusions the results showed that awareness of patients and a few doctors about the first trimester screening tests was respectively weak and middle level, showing that there is an urgent need for greater awareness in this field, regarding the importance of detecting some chromosomal abnormalities prior to birth. objectives the aim of this study was to examine the extent of awareness of physi...

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ژورنال

عنوان ژورنال: Cochrane Database of Systematic Reviews

سال: 2015

ISSN: 1465-1858

DOI: 10.1002/14651858.cd011975